Select Committee on GRAS Substances (SCOGS) Opinion: Calcium acetate, calcium chloride, calcium gluconate, and calcium phytate

The GRAS Substances (SCOGS) Database allows access to opinions and conclusions from 115 SCOGS reports published between 1972-1980 on the safety of over 370 Generally Recognized As Safe (GRAS) food substances. The GRAS ingredient reviews were conducted by the Select Committee in response to a 1969 White House directive by President Richard M. Nixon.

Calcium acetate, calcium chloride, calcium gluconate, calcium phytate

SCOGS Report Number: 45
NTIS Accession Number: PB254539*
Year of Report: 1975
GRAS SubstanceID Code

21 CFR Section

Calcium acetate62-54-4184.1185
Calcium chloride10035-04-8184.1193
Calcium gluconate299-28-5184.1199
Calcium phytate3615-82-5582.6219

SCOGS Opinion:

Extensive studies have been made to determine the nutritional significance of calcium and its salts. Calcium and the acetate, chloride, and gluconate anions are common constituents of food and are metabolized by the normal metabolic processes in man. Phytic acid is a naturally occurring constituent of foodstuffs of plant origin. The very limited use of calcium phytate appears insignificant in light of the natural occurrence of phytic acid. A review of the concentrations of calcium compounds normally present in or added to foods provides no evidence that suggests possible untoward effects at these levels.

In the light of the foregoing, the Select Committee concludes that:

There is no evidence in the available information on calcium acetate, calcium chloride, calcium gluconate, and calcium phytate that demonstrates, or suggests reasonable grounds to suspect, a hazard to the public when they are used at levels that are now current or that might reasonably be expected in the future.

*Complete reports containing details of the safety studies that formed the basis of the opinions and conclusions and are available from the National Technical Information Service (NTIS), 5285 Port Royal Road, Springfield, VA 22161 (703) 605-6000.

Page Last Updated: 09/29/2015
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